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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDC80 All Species: 29.7
Human Site: S319 Identified Species: 50.26
UniProt: O14777 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14777 NP_006092.1 642 73913 S319 A Y M S N L E S H S A I L D Q
Chimpanzee Pan troglodytes XP_512046 642 73980 S319 A Y M S N L E S H S A I L D Q
Rhesus Macaque Macaca mulatta XP_001086615 642 73921 S319 A Y M S N L E S H S A I L D Q
Dog Lupus familis XP_537313 642 73907 S319 A Y M N N L E S H S A I L D Q
Cat Felis silvestris
Mouse Mus musculus Q9D0F1 642 73943 S319 A Y M S N L E S H L A V L K Q
Rat Rattus norvegicus NP_001119742 329 38011 V32 L E L E C E T V K Q E N T R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505423 649 75199 S321 A Y M T N L E S H T G I L D Q
Chicken Gallus gallus Q76I89 640 73723 S322 A Y L A N L E S H T T I L D Q
Frog Xenopus laevis Q8AWF5 638 74459 S317 N Y L T E I E S H S T L L D Q
Zebra Danio Brachydanio rerio Q6DRJ7 632 73198 A315 N Y R C T L E A H K T G L E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17635 590 68894 D291 D D I R K A K D Y L E Q N L H
Sea Urchin Strong. purpuratus XP_001197919 631 72734 E320 N Y L V S L R E H K K T H D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40460 691 80469 Q369 N Y V N A M K Q K S Q E W P G
Red Bread Mold Neurospora crassa Q96U60 743 84837 E395 T L A M Q R T E K Y E N R I Q
Conservation
Percent
Protein Identity: 100 99.6 99.2 92.5 N.A. 83.9 44.5 N.A. 75.5 71.3 56.8 44.2 N.A. N.A. N.A. 21.8 28
Protein Similarity: 100 99.6 99.5 97.1 N.A. 91.5 47.9 N.A. 87.9 84.7 77.4 63.8 N.A. N.A. N.A. 44.8 51.2
P-Site Identity: 100 100 100 93.3 N.A. 80 0 N.A. 80 73.3 53.3 33.3 N.A. N.A. N.A. 0 26.6
P-Site Similarity: 100 100 100 100 N.A. 86.6 6.6 N.A. 93.3 93.3 80 46.6 N.A. N.A. N.A. 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.5 22.7
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 44.6
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 8 8 8 8 0 8 0 0 36 0 0 0 0 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 8 0 0 0 0 0 58 0 % D
% Glu: 0 8 0 8 8 8 65 15 0 0 22 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 72 0 0 0 8 0 8 % H
% Ile: 0 0 8 0 0 8 0 0 0 0 0 43 0 8 0 % I
% Lys: 0 0 0 0 8 0 15 0 22 15 8 0 0 8 0 % K
% Leu: 8 8 29 0 0 65 0 0 0 15 0 8 65 8 15 % L
% Met: 0 0 43 8 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 29 0 0 15 50 0 0 0 0 0 0 15 8 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 8 0 0 8 0 8 8 8 0 0 65 % Q
% Arg: 0 0 8 8 0 8 8 0 0 0 0 0 8 8 0 % R
% Ser: 0 0 0 29 8 0 0 58 0 43 0 0 0 0 0 % S
% Thr: 8 0 0 15 8 0 15 0 0 15 22 8 8 0 0 % T
% Val: 0 0 8 8 0 0 0 8 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 79 0 0 0 0 0 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _